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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b63e2994f65594241e77e13036ed9455165a7b123360a6ff4fabecb41e4e139a' 
  AND token = 'aNW13ta/j3+BSg3/Z/I8FJWFS45g4QMmweThrW2Ddxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}