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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db33eb6e27222073aee14fae7ce3e268659fb7003fa0bc046c315f7ceef56608' 
  AND token = 'L6rBft/r0tbqZ+YrUpCQMtXNYfb/+Y5X9xLMhTUxYj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}