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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e7d72aa99b284960c1eb0b53831af41e4468a2a574f5b2ebb7dcad56486b03' 
  AND token = 'wSWdm9QKsIJXjWrO+ga2S6FWloTE9GAX85Pxms3NbKg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}