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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '62d75a360ff7136230d9ce6fcb7c9c23d11c18bf2e20d80c6afebb8501d1bf63' 
  AND token = 'LuvuUKp0sNaDHonB8qR6NEoXRMu9rz8Z5kjOy8qPkn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}