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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac0ee1ba2a4628fdcdbc563cb57692e07456f7ba00e6468e95f2b6b6d8c4c4e3' 
  AND token = 'OW39c6o+CiIdFWkV6NQk5oMAjU0Skpp5Savg/1QUpjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}