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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4655af08f5fe494ca5c3bf875207f6794977e0d1d7c2d688130d50eed9cde133' 
  AND token = 'UykmEhWo27LH65+YSIxzUWCRrkp5nhdE6z/+0Hzwk+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}