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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eee84cc53df3d3bfb56d8697b0d140ae971aa90a65720369ec70582add0f29a' 
  AND token = 'UBqjq/0JR1UaL48nYjHOLwjGDq491I5d7VSkzl4MAeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}