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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf5307cd4cd3db9ba6419ad15d82d020cd0d0e6628df9de98252ff2bb4ae3603' 
  AND token = 'vyhBbCHjjBG5E0OPjLcQM828QPWZdNg6s3C6aEvFLDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}