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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4412fbb32e8134d4b193aa07171e1340990fa02d1cc583e4c1178aa3ca1d9ee5' 
  AND token = '7o+ozUP2EVTKa97jpa9bXfJANt1OW+hWgaSGAUmqVw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}