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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709e4031fba027b0b875b286956f0b292cb6f9dc4f1902b5f6dadb9616289112' 
  AND token = 'RYLUfWd35ZRmGzCQTae/n+XilLZsm2bPzxsXyuUMCe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}