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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5291dcee48c0f5a8ba72007377875a573c42a586f4fbf3a93d1df4786452f586' 
  AND token = '6jid2ZrlzDoFWg1mEVN9OdODikRfe6qAfMYCpgtB7Cg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}