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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a815e2c21d06ec90c39f2035a8ee1f33e4fc0fe6c445bb9da0aa9365da3597c' 
  AND token = 'hgEUyXImrEIh+PGCRsCTmvlH9XMIOW8tq5NdmZi1tAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}