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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78e947cf0b82d489989c09bb7514f936bca2cdeb997e907f3dc71f6d00821597' 
  AND token = '/WvId3RiBOx+nXNi1SJtZmXq6luXcCvmch6GsIH91Ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}