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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef65e33f1696c82ce658531f43b7dd80678ce131e2a22f2101cc5e0d0af86eac' 
  AND token = 't2Bq0jYOVa+GYuBIXsHNCSePEVpU0jM6o11KD1cXAqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}