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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a59011844956414aada203a27cc91623b0cb984469f8f038c261b5217846826c' 
  AND token = 'K3q54xR6XWcgyC8cERqM+vxCLHQQRhPMrjRWrnU/s2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}