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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b81e9c0c6cfddaa9cff3652de25d586c6ac5ace1877f2273e9e1fce007d25f61' 
  AND token = '+KArXz3zLNpGNgk39AAPPl4IDcftmVYiOxzXlefClM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}