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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b5d6bc88d53d936f2f16a88ceccd246fdf64a53ca579a78f632d9ba3701d679' 
  AND token = 'VU3RRs0+2LUoQdnOGAbR5n4S1v/Mra5ZH5jCF5uhKio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}