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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f2699215ecd0a926f946ae79cc7a1c0ca03d2819e47518f29a06705c114e4d8' 
  AND token = 'tLYtoI+qcUN+3Eo0nPEvIDQYGB7DHdGYeDAlk4zer6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}