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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ae07ec18d6651dd3c146e2941fb1b917e12d9af3d72723ebc59e799b1ef0651' 
  AND token = 'PiEP1hMtwEEExbIg9t1+ezccApztOvMB2uA6Ko5rADo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}