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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d0227f16c645159373df2cba4f6e84e5061036b4dd07fb8562c2dfb4ca332a4' 
  AND token = 'gV8i80eyHP/VX0qn/Lq8gYGZtlE2EwfFEWWv2kvV6a0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}