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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6f28ae301407bd56ae71d5e83be8d1966d8a2a23ec54465038d5014b90196a8' 
  AND token = 'KMqmXjom/d/8w77U7avT0HEaV4UjmOIGIpA7B1bLsDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}