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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fbee2fe56de49a0e847b86fef149813fde80fbf3ad5949bf57d29f99267a7562' 
  AND token = 'CmrXpYGa0Nrg9Fob1ykrBBO7UgE+utyfBTYd5QG3YUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}