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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72bb18f81e2035fed0558f6e717b4ea202fd083dbf4d03bc83d78e66be0ea40c' 
  AND token = '21czQ7YRHFsZdkpL0yt94UpLnC5hYw9KP1w7994i0Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}