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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b27a4733c3b7f9b089c8102da54faea96b107322192d0f1e6106bacb1afac7a' 
  AND token = 'sfPEzShjl5WqZ+KDVR2rXqLZEz6sDQsWHdjcNmeiaH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}