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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dc0eb33d6b3466e98f5ac7b797cc2dd1b57c45c7e49d85148c3ce976cbde443' 
  AND token = 'kMneteVDOo/28G9SAwsKhhgwig60E4EtY2LvCgPC9+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}