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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0750cd7eb5448b780c9ea15fc91fcea124586f3843b80d9ff2a1e9bc5ff7fc9f' 
  AND token = 'jl+fLOAX1GyWtWJWxDngO832rpe0aNxU6o6ks02Gg20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}