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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5824bf20209ae2814f411bbf4b9819aac6863b2416a33af575e5b8fffea9f52b' 
  AND token = 'nYFLXk/04b5tqDw7mRnSOzzDmT+1BkSjaoElZY1kPns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}