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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a66995dacefd3a009baede901f9f520534f750cef4533754f75c940046d5683' 
  AND token = '0+JvH0xLrPfXuvKumwB7DQYmzlqrRIcf5VIRVdfxrxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}