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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b53ab25c9d88993d2cabf718f83b2f01ded7d45d36fa863f5af73c9bb03e7f' 
  AND token = '6qFq3oeoGlWLseIjq1VGHZpByaC+tB23BO6ZC3hJLPc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}