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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '078f863fc5a5c6b1f86a415b4056092e4aaa91ec7593300b5f71b8305b00e416' 
  AND token = '+AxhyOMsjWHX9d0i9aIF8/MCXLksBFAIIdlfBtTHiM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}