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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e9e50c33d2fb848f30991979ea0068dc0b632aa9764da7e89f0515b63e06b7' 
  AND token = 'fFIvDwq+pDpunDWeHVy2/QN3ZXoN40d02VS0t9thxFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}