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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '518aea8c06e2688173f3c07a8900ea13f728ae4ed48bff1b9101234d9763540a' 
  AND token = 'MUo4Uqlld567N+eIxhSDTOW+v5EOCKUEW6g9tSPyIfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}