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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36e9b3a9c12442ced28da670ac07f0d80a9b159d46fb56aa555aa58eb8114107' 
  AND token = 'wt7dgICxAjPMPXKI2SVqGd8bSNoqfCBFcXjrHx1cEPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}