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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c72dfd27cf222d77f2281396a3541d42955df117a86dae74c113c75490f55f10' 
  AND token = 'EifMzQ800lkmS1u6tzodSX/Ug3l3gs+T8JMhQJxgfeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}