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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b8e2a1c79b9561e5d9125b4d1330e4768a2857ba9c9a4e9dea73d052235bf4' 
  AND token = 'pMz5HLhxzgDuwNoq/CR39/4F3wc6eXq/G+QaV+0af/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}