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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4295c4b4f13a76f3b999762e54d45f3af34880d19e071e5231cbc1ccad4a1c3' 
  AND token = 'B5GhfK9oxuO3BEWeCe4PCyx6hBzf6dxRYv+FjDKiOtA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}