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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a422c2969d9d393c1bf92a7d5219bf779f36ae657d8799453558fa12ed12204c' 
  AND token = 'DWCo9oIb7A8U9b01PPMWjklO5a/UnUsJfWTtzT6OoS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}