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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1be10788d29bbfe7537f46da7f78674f74f9e53e934b9a117439a7f352adccda' 
  AND token = 'a0GnDPRO0oTdu0MfoUFYIvezyAeKtimzULxVMGwU484=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}