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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76d6d253ce06cff3d81fb608eff34ae7635a489b1edbecb90be89da56160baa4' 
  AND token = 'OPE/4fa8c/J1cdi2iZsw+5alCskC48GKcoOaoxN+yLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}