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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd588dda1a138c402e3d74deb7b35a8191ad2371143616dde58e3744fb4289ba' 
  AND token = 'GuIy5XFO1dK0Kq4pJHirZOpflH9fWO+R4mSO9Ovn0H4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}