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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '205d4d302de021b7051e785156f5cb9227f51619399211f3e9915bc790cb9a46' 
  AND token = 'O1oxv0MnGI4aGy55Yu0h6Iex8PMfaAKncu+1HbR6TPk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}