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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed73676a109760e3856a8e8facadfed8c026ad1afbd4667a694face2d1e2c6ba' 
  AND token = 'l4UODpVjQ6awKOpL1vJcLf6p8NFVXZZK7KqkvmDkJ/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}