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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e277507e26f4101211562dfdfc1eb6f8d40df853beb811f32feb7a26427729f7' 
  AND token = 'Id65kgYRjns3p84ZEruca6ej/KILcE5/TYHQCa0vOls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}