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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0025253006e8a309c51dcca5480bdc08e4a640f7fb797ffe1e76279e0f58f9bf' 
  AND token = 'BkLC8qgQmfTrijCqRcAYMTEEFM6WbXeSaoFvXcBlj4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}