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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a338f01419f4a0a885d8b430fccc8d39de3a1f5753118426cb18b419f0f9bc22' 
  AND token = 'HGKP5X5fiykwttTW7/HmOVnHI30h8ntpKBpgHQ1qRQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}