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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a57578939f061ef0d4bf665f7412bb3f883a06f5c432cb80b658e3143eb0c5b6' 
  AND token = '2j8ifxydaDUOY2bWxMeDJ46N3o8gny0RXn2wz2gor+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}