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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e19a168bf4c3cb2ce13eb17f0aa18f347736787a8f84ec5f3b26189655b86dc' 
  AND token = 'CKv4VbK9W5ltI/aEsT3Q0Y22pRb1n+fX1QaRVP8LMHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}