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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6ee8765875120cc2dc7c9eaac904aae0091e49db5b2b9c781274eea396a71b6' 
  AND token = '8hxm2aRQpQespIxUE/PVEJDb1DrgnM6ggWMTb2X3SK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}