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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd52d939d7e8852edd9921b94c838a01bc7eb2bb3d85f1d84d8763a02e345378f' 
  AND token = 'C6iWzSdVbu7ARIR4K9DxoTAAX5yXSB9D36zetLvc3/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}