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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49e334c479876ab923227d06b22e608f0d1dcfe4425141a4502b9db93c9832c4' 
  AND token = 'YKwv383aTR9ykiqIyddH3QOjIIAv6F9Lz3zC0jCXb3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}